BiomeNourish™ difference
The first and only prescription base formulated for the vaginal and vulvar microbiome.
Based on patented Bio-Match® Technology
Based on patented Bio-Match® Technology
Most prescription bases weren’t designed for delicate vaginal tissue. They can irritate sensitive skin, disrupt the natural pH balance, and damage the protective microbiome. Disruptions in the microbiome leave you more vulnerable to potential pathogens and lead to recurrent infections like BV, yeast infections, and ongoing vaginal irritation.
Petroleum-derived ingredients like propylene glycol
Formulated for use on vulvar and vaginal tissue
Hyperosmolar
Iso-osmolar
Not pH matched
pH + osmolality matched
Can irritate tissue
Designed for vaginal tissue and microbiome compatibility
Hyperosmolar prescription bases can pull moisture from tissue, cause surface shedding and weaken the barrier function.
Petroleum-derived ingredients like propylene glycol
Formulated for use on vulvar and vaginal tissue
Hyperosmolar
Iso-osmolar
Not pH matched
pH + osmolality matched
Can irritate tissue
Designed for vaginal tissue and microbiome compatibility
Hyperosmolar prescription bases can pull moisture from tissue, cause surface shedding and weaken the barrier function.
BiomeNourish™ is the only prescription base formulated with patented Bio-Match® Technology to support the vaginal and vulvar microbiome. Available as both a cream and in suppository form, it provides a foundation that helps create the conditions needed for healing, comfort, and long-term balance before, after, or alongside treatment.
The BiomeNourish™ Prescription base restores the tissue barrier, supports healthy pH, and protects the microbiome.
The BiomeNourish™ Prescription base restores the tissue barrier, supports healthy pH, and protects the microbiome.
In three longitudinal pilot studies involving pre- and post-menopausal women with a history of recurrent BV, the Bio-Match® hygiene system was associated with statistically significant and sustained reductions in vaginal pH, along with measurable improvements in self-reported irritation, discomfort, and odor.
These findings align with how the BiomeNourish™ delivery system is designed: to support the vaginal microbiome and help maintain vaginal health through a sustained low pH that promotes balance, comfort, and resilience.
Figure 1. In three pilot studies vaginal pH fell significantly over a 12-week period
Figure2. Self-reported vaginal odor and irritation improved across the study period
Chronic vaginal conditions often require long-term attention. Addressing an immediate symptom doesn't resolve the underlying imbalance. Maintaining a healthy vaginal ecosystem starts with a low pH, Lactobacillus-rich microbiome. By helping sustain an acidic pH, BiomeNourish™ supports the conditions associated with lasting vaginal health.¹ When that balance is repeatedly disrupted, women often experience recurring symptoms including odor, irritation, dryness, and discomfort.²
Bio-Match® technology was developed with this in mind: not as a one-time intervention, but as a system designed to work consistently with the vaginal environment, supporting the conditions that keep it resilient.¹
Healthy vaginal tissue depends on moisture balance. Formulas that are hyperosmolar can pull water from delicate cells, leading to dryness, irritation, and barrier disruption. Bio-Match® is designed with iso-osmolar balance to help support comfort, hydration, and tissue integrity.
Disease-causing bacteria thrive in a higher pH environment, while beneficial bacteria flourish when pH is low and stable. Maintaining a healthy pH over time is the most important factor in restoring and sustaining vaginal microbiome balance.
Protective lactobacilli help maintain the vaginal environment by supporting healthy acidity and microbiome balance. Bio-Match® is designed to work with these beneficial bacteria, helping to support long-term vaginal wellness and microbiome resilience.
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